Damian G Downey Selected Research

tezacaftor

1/2022	Efficacy and safety of elexacaftor plus tezacaftor plus ivacaftor versus tezacaftor plus ivacaftor in people with cystic fibrosis homozygous for F508del-CFTR: a 24-week, multicentre, randomised, double-blind, active-controlled, phase 3b trial.
11/2019	Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.

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Damian G Downey Research Topics

Disease

26	Cystic Fibrosis (Mucoviscidosis) 02/2024 - 07/2012
4	Lung Diseases (Lung Disease) 10/2023 - 01/2017
3	Inflammation (Inflammations) 01/2022 - 09/2020
3	Infections 09/2021 - 12/2015
2	Pseudomonas Infections 10/2021 - 01/2017
2	Persistent Infection 09/2021 - 01/2018
2	Pneumonia (Pneumonitis) 01/2021 - 01/2018
1	Rare Diseases (Rare Disease) 10/2023
1	Bronchiectasis 01/2023
1	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 01/2022
1	Psychotic Disorders (Schizoaffective Disorder) 01/2022
1	Headache (Headaches) 11/2021
1	Exocrine Pancreatic Insufficiency 01/2017

Drug/Important Bio-Agent (IBA)

7	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 10/2023 - 01/2018
5	Anti-Bacterial Agents (Antibiotics)IBA 09/2021 - 07/2012
4	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2016
3	elexacaftorIBA 10/2023 - 11/2019
2	trans-crotonin (CTN)IBA 02/2024 - 08/2021
2	ivacaftor drug combination tezacaftorIBA 10/2023 - 01/2021
2	ivacaftorIBA 01/2022 - 11/2019
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 09/2020
2	tezacaftorIBA 01/2022 - 11/2019
2	Anti-Infective Agents (Microbicides)IBA 09/2021 - 10/2020
2	ChloridesIBA 11/2019 - 01/2017
1	Nucleic AcidsIBA 10/2023
1	C-Reactive ProteinIBA 01/2023
1	acebilustatIBA 11/2021
1	riociguatIBA 11/2021
1	leukotriene A4 hydrolaseIBA 11/2021
1	Oxygen (Dioxygen)IBA 10/2021
1	Azithromycin (Zithromax)FDA LinkGeneric 10/2021
1	lenabasum (ajulemic acid)IBA 01/2021
1	CB2 Cannabinoid ReceptorIBA 01/2021
1	CannabinoidsIBA 01/2021
1	AlginatesIBA 10/2020
1	OligosaccharidesIBA 10/2020
1	PowdersIBA 10/2020
1	Sodium Chloride FDA LinkGeneric 01/2020
1	Enterotoxins (Enterotoxin)IBA 01/2020
1	Lysine (L-Lysine)FDA Link 11/2017
1	Aztreonam FDA LinkGeneric 11/2017
1	ThymidineIBA 01/2017
1	Poly TIBA 01/2017
1	GuanineIBA 01/2017
1	IronIBA 12/2015
1	Heme (Haem)IBA 12/2015
1	HaptoglobinsIBA 12/2015
1	Chelating AgentsIBA 12/2015
1	Protein Isoforms (Isoforms)IBA 12/2015

Therapy/Procedure

7	Therapeutics 10/2023 - 09/2020
1	Lung Transplantation 10/2021
1	Polypharmacy 10/2018